Posts Tagged ‘Studied’
Cholesterol Drug Lovastatin Being Studied As Potential Mesothelioma Treatment
Researchers recently uncovered the potential of a cholesterol drug, introduced in the 1980s, that may offer mesothelioma victims an effective treatment for the deadly and incurable cancer. The drug, Lovastatin, is used to treat and control high levels of cholesterol among patients.
Early on, scientists found that in initial studies of the drug, dating back 20 years, it had an unexpected and very powerful effect on killing cancerous cells within humans. At that time, however, the anti-cancer effect was considered too risky to continue studying because of the extremely high doses that were needed to be given to a cancer patient. Researchers put the study on hold, according to news reports, until recently when scientists at a Nashville, Tenn., clinic started providing the drug to pleural mesothelioma patients.
Details of Lovastatin and its Cancer-Killing Potential
Researchers have given little notice to Lovastatin as a treatment for mesothelioma cancer even though a stage-four melanoma patient had received treatments of Lovastatin in 2000 and currently remains cancer-free, nearly nine years later. While researchers are unsure that they can find the same success of the melanoma patient, the use of Lovastatin may potentially reduce or slow the cancerous production of mesothelioma cells, which can kill an individual within as little as one year after symptoms appear.
A study published in the American Journal of Respiratory and Critical Care Medicine found that the cholesterol drug induces apoptosis on mesothelioma cells. Apoptosis is also described as programmed cell death, according to the Reproductive and Cardiovascular Disease Research Group. Apoptosis occurs when a stimuli is introduced to a variety of cells in which the cells begin to commit cell suicide. The study looked at the morophologic changes, histologic evidence of nuclear condensation and degeneration, and flow-cytometric analysis of DNA content of the mesothelioma cancer cells treated with Lovastatin and determined it a potentially sufficient treatment for mesothelioma.
What is Lovastatin?
Lovastatin is part of a group of drugs known as HMG-CoA reductase inhibitors (statins). The drugs decrease the production of bad cholesterol within the body. It is often prescribed to patients as an oral pill that is taken in low-doses — once every four weeks.
Lovastatin does have reported side effects, which have not been fully studied on mesothelioma patients, however, according to the National Library of Medicine (NLM) the side effects include:
* hives, rashes and itching
* loss of appetite
* flu-like symptoms
* nausea as well as pain in upper right part of stomach
* extreme tiredness
* yellowing of skin and eyes
* lack of energy
* difficulty breathing and swallowing
* swelling of face, throat, tongue, lips, eyes, hands, feet, ankles and
* lower legs/calf muscles
* muscle pain, tenderness or weakness
* fever
* unusual bleeding or bruising
* hoarseness
* constipation
What to do If Diagnosed With Mesothelioma
Mesothelioma cancer has become increasingly prevalent in the United States and around the world. Individuals who were exposed to a mineral known as vermiculite containing deadly asbestos may have had the condition for 20 or more years without any signs of the cancer within their bodies.
Once researchers began discovering the link between asbestos exposure and mesothelioma, asbestos was banned in the United States and around the world. However, shipments of asbestos are still being imported into the United States and millions of Americans remain at risk for exposure because of the prevalence of asbestos in many homes, apartments, schools, universities, hospitals and government buildings.
Those who have suffered from mesothelioma cancer or feel they may have been a victim of asbestos exposure have the ability to consult a legal professional for a potential mesothelioma lawsuit. Such litigation may appear overwhelming to a victim, but can potentially offer monetary compensation for the heavy expenses associated with receiving mesothelioma medical treatments. Consulting a mesothelioma attorney is often a free legal service and may add peace of mind for mesothelioma victims, their families and friends.
Learn more about mesothelioma and other various treatments at http://mesothelioma.legalview.com/ . Also, visit the LegalView homepage (http://www.LegalView.com) and learn about the Levaquin side effects or the Digitek digoxin recall.
Active Symptom Control for Mesothelioma Studied in Chemotherapy Treatment
Although mesothelioma cancer has no current cure, many medical professional believe that chemotherapy can be a successful treatment of symptom control of the condition, however, this continues to be debated, according to a study from The Lancet, a British Journal.
Researchers studied 409 patients all of which were suffering from malignant pleural mesothelioma in different parts of the world. According to the study, patients received either an active symptom control treatment with one of two chemotherapy medications or just an active control treatment. “The active symptom control treatments included steroids, bronchodilators, analgesic medications and palliative radiotherapy,” according to the study.”
Following the study, the patients with both treatment options were compared and, according to researchers, “the addition of chemotherapy to active symptom control presented no significant benefit or advances in survival rates or quality of life” among mesothelioma victims.
Diagnosing and Understanding Chemotherapy, Mesothelioma?
Mesothelioma is a disease in which malignant cancer cells develop in a thin layer of tissue that lines the chest cavity covering the lungs, which is also known as the pleura, or the peritoneum, which is the tissue lining the abdomen and most of the organs, according to the National Cancer Institute (NCI).
The American Cancer Society (ACS) describes chemotherapy as a treatment for cancer; it is often given to a patient when cancerous cells spread rapidly to healthy cells.
Doctors must adequately evaluate a patients age, health and stage of cancer prior to administering chemotherapy. Chemotherapy is actually given to a patient not as a treatment to cure mesothelioma, but it is administered for several reasons such as:
* stop growth and spreading of a cancer, to control the cancer
* minimize or shrink tumors – this method is also known as neoadjuvant chemotherapy
* palliative chemotherapy in which pain and other symptoms are meant to be reduced
* the destruction of microscopic disease that remains after a surgical procedure, also known as adjuvant chemotherapy
Chemotherapy is administered either as a catheter placed into a large vein in the body or a catheter attached as a port that is placed into the chest area under the skin for a period of time.
Living With Mesothelioma
Unfortunately, victims of mesothelioma continue to receive setbacks for their life-threatening condition, as there are currently no successful treatments for the deadly cancer.
However, an individual has the opportunity to participate in an array of clinical trial treatment groups as well as the opportunity to develop a mesothelioma lawsuit to derive monetary compensation as a means of repayment for the condition, which is often associated with extremely expensive medical bills.
Consulting with an experienced medical or personal injury lawyer may be able to provide insightful details as to developing a mesothelioma lawsuit to receive monetary compensation for costly medical bills.
It is important for mesothelioma patients to receive additional advice and assistance by visiting http://www.mesothelioma-law-now.com or http://www.LegalView.com/ . Here, patients can also learn about additional topics ranging from Avandia dangers to Nephrogenic Systemic Fibrosis treatments.