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Malignant mesothelioma is a very rare form of cancer, which occurs when malignant cancer cells collect in the thin layer of tissue that lines the chest cavity and protects the lungs, also called the pleura. It can also be found in the lining of the abdomen, or the peritoneum. Mesothelioma is almost always caused by exposure to asbestos. www.asbestos.net

Malignant mesothelioma is a type of cancer that is quite rare; it affects only the thin wall of cells that line the internal organs and structures. This lining is called the mesothelium and malignant mesothelioma can manifest itself in three main ways. It can be pleural which affects the lungs, peritoneal which affects the abdominal cavity wall and pericardial which affects the lining in the heart. Experts believe that there is only one way to contract malignant mesothelioma and that is through exposure to asbestos.

Asbestos is a naturally occurring mineral that is highly toxic to humans yet was once used in abundance in the building and construction trades. It was used as it has a very high tolerance of heat and it is remarkably strong, it was also very cheap. It is made of fibres which are microscopic and can be airborne when ceilings covered with asbestos crack or when it is otherwise exposed to the air. When fibres of asbestos get inside the body they cannot be broken down or expelled and this will result in serious scarring of the mesothelioma and inflammation. Once this scarring occurs it is only a matter of time before malignant mesothelioma takes hold in one of its various forms.

Symptoms of malignant mesothelioma can initially be quite hard to spot as they can be quite unnoticeable. As a result they can be passed off as being day to day illnesses and this can cause even more problems as this delay gives malignant mesothelioma even more time to take hold of a person. It has been known for people with malignant mesothelioma to live with their symptoms for up to six months before they seek medical help with them. Symptoms of the various forms of malignant mesothelioma can include – shortness of breath, weight loss, nausea, vomiting, persistent coughing with or without blood in it, abdominal pains, stomach pains, chest pains, pain in the lower back and in some cases swelling of the face and arms and a loss of sensory capabilities. As these symptoms are so wide ranging and often seemingly unconnected it is no wonder that it can be difficult to obtain a correct diagnosis. Experts now recommend that anyone who has had prior exposure to asbestos at some point in their lives gets checked out for malignant mesothelioma even if they feel fit and well. Doing this could vastly extend a person’s life who could go on to be diagnosed with malignant mesothelioma.

Treatment for malignant mesothelioma can vary and surgery should only be an option if the disease is diagnosed in the very early stages. Otherwise it is more common for a person to undergo chemotherapy or radiotherapy to attempt to control the malignant mesothelioma. Although there is no known cure for malignant mesothelioma it can be controlled for some time if it is caught in time. Otherwise the outlook is not particularly positive and the best that many people with malignant mesothelioma can hope for is to be able to manage their symptoms and pain with painkillers and other medication.

A complete information on Diffuse Malignant Pleural Mesothelioma. financeliberty.com

Mesothelioma treatment and treatment options for advanced malignant mesothelioma are not limited to surgery and chemotherapy. Increased awareness of mesothelioma and other asbestos-caused diseases has led to an increase on medical research to cure and control asbestos-caused cancers and related asbestos heart and respiratory diseases. Although chemotherapy and surgery are the most common forms of treatment, participating in clinical trials can provide you with alternative mesothelioma treatment options.

Perhaps the most common clinical trials and mesothelioma treatment options for advanced malignant mesothelioma involve chemotherapy and drug combinations. Drugs produce a medical benefit by themselves, and they can produce a different benefit when combined with other drugs – a chemical reaction that produces a third result. Advanced malignant mesothelioma clinical studies with Cisplatin, now often used with chemotherapy, proved Cisplatin to be effective. Mesothelioma clinical trials with Gemcitabine proved Gemcitabine to be ineffective. However, mesothelioma clinical trials using Cisplatin and Gemcitabine together are proving to be even more promising. Finding the right drug combinations to slow tumor growth and contribute to improved pain management is one of the fastest paths to wide-spread availability of new mesothelioma treatment options.

Anti-angiogenic therapy is a biological therapy based on interfering with the blood vessels that the cancer needs to survive. Advanced malignant mesothelioma patients have a higher vascular endothelial growth factor than patients with other cancers. Anti-angiogenic therapies focus on natural body substances that affect the mesothelioma cancer’s growth, including the use of drugs made of these substances to inhibit cancer growth factors.

Immunotherapy is also classified as a biological therapy. Immunotherapy, as the name suggests, concentrates on building immunity to the cancer cells. Immunotherapy can involve vaccines, and in cases of mesothelioma, these are likely to be injected in the pleural region. IL-2 is made naturally by the body, and clinical trials have demonstrated its success at treating mesotheliomas in the early stages, mesothelioma stages one and two, but not effective in treating advanced malignant mesothelioma.

Photodynamic therapy has gained increase attention in many medical fields for various treatment options, including mesothelioma treatment. Photodynamic therapy uses light and heat to kill cancer cells. Unfortunately, clinical trials have not been successful with advanced mesothelioma patients, nor patients in the mesothelioma patients in stages one and two. It has been successful in treating other cancers.

Gene therapy, also referred to as molecular therapy, is an exciting and relatively new field of research being applied to mesothelioma treatment. Oncogenes contribute to the fast spreading of the cancer cells and tumor suppressor genes stop cells from spreading. The medical premise is to replace the genes in cancer cells with healthy genes. Gene therapy is also a biological therapy and explores using the body’s natural substances to treat mesothelioma stages.

Mesothelioma treatment for advanced malignant mesothelioma is slowly finding new mesothelioma treatment options. It takes years to evaluate the clinical significance of a clinical trial and medical research to prove that a mesothelioma treatment option is a promising and viable alternative. Thorough medical research on mesothelioma treatment contributes to safe medical treatment options being widely-available to the public. Mesothelioma in any of its stages is dangerous, but with researchers working together, mesothelioma treatment options will be safer and mesothelioma research will someday find a cure.

Peritoneal mesothelioma is less common than pleural mesothelioma, but both of these typically malignant mesotheliomas can be just as tragic. Peritoneal mesothelioma begins in the abdominal cavity, as opposed to the lungs and pleural areas of pleural mesothelioma. “Peritoneal” means it has to do with the peritoneum, which is a membrane that surrounds the abdominal area. “Pleural” refers to the pleura which is a membrane that surrounds the lungs. There is also a “pericardial” mesothelioma which targets the heart membrane first.

The lungs, abdominal area and heart all have a membrane made up of mesothelial cells, named the mesothelium. A cancerous attack of these membrane areas are mesotheliomas. Asbestos is the cause of peritoneal mesothelioma, pleural mesothelioma and pericardial mesothelioma in well over 90% of the cases. There are a few rare recorded cases of malignant mesothelioma when asbestos exposure was not identified. If you have been exposed to asbestos, there is a high chance you will suffer from an asbestos-caused disease such as asbestosis or pleural plaques. However, not all asbestos-caused diseases are fatal.

Peritoneal mesothelioma, pleural mesothelioma and pericardial mesothelioma can be fatal malignant mesotheliomas which spread uncontrollably, or they can be benign, when the tumor stays where it is and can likely be removed. Unexplainable weight loss is a mesothelioma symptom which may occur in as many as 90% of benign and malignant mesothelioma. Generally, benign mesothelioma tends to show less symptoms than malignant mesothelioma. Mesothelioma symptoms for peritoneal mesothelioma almost always includes abdominal pain. This is because there is excess fluid between the peritoneal membrane and the abdomen walls. Pleural mesothelioma has excess fluid in the pleural area and this causes shortness of breath and chest pain.

The mesothelioma symptoms of pleural mesothelioma and pericardial mesothelioma are not as outwardly visible as the symptoms of peritoneal mesothelioma. In peritoneal mesothelioma, the abdomen can appear larger. Tumor masses may be visible, but external tumor visibility only occurs in a minority of peritoneal mesothelioma cases. Nausea is a common mesothelioma symptom with peritoneal mesothelioma, and the abdominal area will also be very tender.

In a healthy peritoneal area between the membrane and the wall, the peritoneal fluid helps the intestines move food. In peritoneal mesothelioma however, excess fluid causes bowel obstruction. The mesothelioma symptoms of extra fluid and bowel obstruction both contribute to abdominal pain. The bowel obstruction can also produce mesothelioma symptoms of constipation and diarrhea. Many peritoneal malignant mesothelioma patients have reported mesothelioma symptoms of a burning sensation in the abdomen. Mesothelioma symptoms for peritoneal malignant mesothelioma may not surface for 20-30 years after asbestos exposure, but it generally surfaces sooner than pleural mesothelioma.

Peritoneal mesothelioma is fortunately rare, however its rarity sometimes makes it harder to diagnose. The symptoms are similar to hernias and gall bladder problems, and identifying peritoneal mesothelioma in a CT scan is difficult. The medical industry is aware that asbestos-related diseases will be escalating over the upcoming years, and treatment for peritoneal malignant mesothelioma is undergoing many clinical trials. If you have been exposed to asbestos and have unexplainable abdominal pain and are experiencing unexplained weight loss, begin preliminary testing for peritoneal mesothelioma. The sooner the testing begins, the higher the chances for symptomatic relief, and hopefully today’s mesothelioma clinical trials will lead to a mesothelioma cure in the future.